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Engineering | Safe Engineering

Hydrogen Gas

What are the hazards of hydrogen gas? Hydrogen gas (CAS# 1333-74-0) is not toxic to breathe, although it can function as an asphyxiant if it displaces enough breathable air. Hydrogen gas has a low LEL and a broad flammability range, so the flammability/explosivity...

HF Acid, Ammonium Bifluoride, and Other Soluble Fluorides

I've worked with corrosives before. What makes HF and other fluorides special? The chemicals below, and related soluble fluoride salts, release fluoride ions (F-): ammonium fluoride (CAS# 12125-01-8) ammonium bifluoride (CAS# 1341-49-7) hydrofluoric acid (CAS#...

Dimethyl Sulfoxide (DMSO)

DMSO is the classic polar aprotic solvent. It's used in lots of known reactions. Why should I worry? DMSO decomposes with heating, and the decomposition products catalyze further decomposition, resulting in a runaway reaction that has caused explosions resulting in...

Thiols, Mercaptans, and Other Stench Chemicals

What is a stench chemical? Stench chemicals have an extremely foul smell that is detectable by the human nose in parts-per-billion amounts, depending on the compound. While the stench may not be known to have toxic effects, it can still negatively impact laboratory...

Chloroform, Dichloromethane, and Other Halogenated Organic Compounds

Chloroform is a common solvent, starting with NMR samples in sophomore-level chemistry. Why should I worry? Chloroform, dichloromethane, and many other halogenated organic compounds readily pass through nitrile gloves. This means that the disposable gloves most people...